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Welcome to PLIER: Pathway-Level Information ExtractoR. All you need to use PLIER is a gene expression matrix. The requirements are: The data should look like this
Sample1 Sample2 Sample3
ACTB 1 2 3
TP35 4 5 6
EGFR 7 8 9
Email We will send an email when the results are ready
Prior Knowledge Sources


Marker genes for cells found in blood from diverse sources
Curated pathways from Reactome and KEGG
Chemical and Genetic Perturbations from MSigDB
User supplied genesets, can use alternative gene nomenclature, click checkbox to view an example
Gene Expression Matrix
k Number of latent variables to return. Leave blank for automatic determination
frac Fraction of latent variables that use prior information
Default recommended
Verification code Click the picture again if you can't see it clearly
There is no distinction between the lower case letters and capital letters